Computational Biologist / ML Scientist Job at Amber Bio, Sunnyvale, CA

bXUyMEl2K2duS3hIUHduVkU0aWk4dnh0elE9PQ==
  • Amber Bio
  • Sunnyvale, CA

Job Description

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA writing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. Multiple openings are available on a rapidly growing team. As an early team member, you will have the opportunity to contribute to strategic planning and future hiring. If you are interested in building a new frontier in genetic medicine, please apply through or directly on our website ().

If you are a skilled Computational Biologist or ML Scientist with a passion for applying machine learning approaches to (one of: model/design/engineer) biological sequences, we encourage you to apply and join our innovative team.

Job Description: Computational Biologist / ML Scientist

Responsibilities include:

  • Implement state of the art methods to predict RNA and protein function from sequence.
  • Analyze and preprocess experimental data, including DNA, RNA, and protein sequences, high throughput screening data and structural data for model training and validation.
  • Plan and execute machine learning experiments, and set milestones and timelines to achieve research objectives.
  • Collaborate with wet lab scientists to align ML experiments and integrate model insights into the design process
  • Fine-tune models using custom datasets and external resources to achieve high predictive performance.
  • Collaborate with gene editing and molecular biology experts to integrate model insights into the design process.
  • Stay updated with the latest advancements in machine learning techniques, RNA/protein structure prediction, and gene editing technologies.
  • Publish results in relevant conferences and peer-reviewed journals.
  • Design, build, and maintain computational pipelines to process, analyze, and interpret next-generation sequencing (NGS) data, including variant calling and differential expression analysis.

Qualifications:

  • Ph.D. in Computer Science, Bioinformatics, Computational Biology, Molecular Biology, or related fields. Strong academic background in machine learning and molecular biology is preferred.
  • Minimum of 2 years of practical experience in developing machine learning models, with a focus on RNA and protein structure prediction, acquired during PhD studies or a post-graduate role.
  • Proven track record of addressing high impact questions in biology using statistical and machine learning techniques.
  • Understanding of gene editing techniques, such as CRISPR-Cas9.
  • Experience with RNA and protein structure prediction tools and databases (e.g., Rosetta, RNAfold, PyRosetta, AlphaFold).
  • Proficiency in Python and PyTorch / TensorFlow and other bioinformatics tools.
  • Excellent communication skills and the ability to collaborate effectively with technical and non-technical teams.
  • Strong analytical skills with the ability to design creative solutions for complex molecular challenges.

Preference will be given to those who display:

  • High motivation, with a strong work ethic and dedication to generating impact.
  • Long-term personal vision with defined career goals.
  • High EQ with team-oriented thinking.

If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.

Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.

Job Tags

Similar Jobs

CSL Behring

Manager Coagulation Products, Plains Job at CSL Behring

 ...Job Description Territory- Iowa/Nebraska/Kansas City Manager of Coagulation Products (MCP) is responsible for promotion and utilization of CSL Behrings hemophilia product portfolio and for managing all aspects of territory business development. The MCP will... 

Nationwide Therapy Group

Travel Wound Care Nurse - $2,354 per week Job at Nationwide Therapy Group

 ...Nationwide Therapy Group is seeking a travel nurse RN Wound Care for a travel nursing job in Fort Defiance, Arizona. Job Description & Requirements ~ Specialty: Wound Care ~ Discipline: RN ~ Start Date: ASAP ~ Duration: 13 weeks ~40 hours per week ~ Shift... 

Foxquilt

Sales Development Representative (SDR)- Partnerships Job at Foxquilt

 ...Job Description Job Description: Sales Development Representative (SDR) - Partnerships About Foxquilt Foxquilt is a leading North American insurance technology company focused on empowering business owners through embedded, customizable insurance options. Foxquilt... 

Spring View Hospital

Travel ICU Registered Nurse - $2,203 per week Job at Spring View Hospital

 ...Specialty: Critical Care Number of Openings: 2 Shift: Dayshift Weekend and Nightshift Weekend (Friday-Sunday) Weekly Guaranteed Hours...  ...: Yes, Med Surg when ICU is closed Would be only ICU nurse in house if 2 patients or less (with supervisor available for support... 

Rozier Hardt McDonough PLLC

Patent Litigation Attorney Job at Rozier Hardt McDonough PLLC

 ...Join our growing team. Rozier Hardt McDonough is a boutique patent litigation firm with offices in Atlanta, Austin, Denver, and Washington DC. We are searching for a driven and experienced Senior Associate or Counsel to work out of either our Denver, Atlanta, or Austin...